A SYNERGISTIC TRIAD OF CHEMOTHERAPY, IMMUNE CHECKPOINT INHIBITORS, AND CALORIC RESTRICTION MIMETICS ERADICATES TUMORS IN MICE

A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice

We have recently shown that chemotherapy with immunogenic cell death (ICD)-inducing agents can be advantageously combined with fasting regimens or caloric restriction mimetics (CRMs) to achieve superior tumor growth control via a T cell-dependent mechanism.Here, we show that the blockade of Pillow Block Bearing the CD11b-dependent extravasation of

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